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Tag Archives: hydroformylation
Switching the acid, one palladium catalyst swaps between alkyne hydroformylation or semihydrogenation (an article review)
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In drug discovery, chemodivergent reactions have recently attracted great interest because of their involvement in the synthesis of libraries of small molecules. The concept of diversity-oriented synthesis relates to the selective formation of various well-defined products from only one readily available starting material. This can be achieved by steering the reaction’s selectivity through fine-tuning of […]
Read MoreSelective hydroformylation by remote control
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A joined research paper by InCatT and the University of Amsterdam has recently published as HOT PAPER in Chemistry European Journal describing the selective hydroformylation by remote supramolecular control. Yes, also fatty acids! Regioselective Hydroformylation of Internal and Terminal Alkenes via Remote Supramolecular Control by Pim R. Linnebank, Stephan Falcão Ferreira, Alexander M. Kluwer, Prof. Dr. […]
Read MoreExpending catalyst space using a new ligand synthesis (an article review)
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The testing of libraries of phosphorus ligands is at the core of catalyst screening for the optimization of industrially relevant process. Among these processes, hydrogenation, hydroformylation and cross coupling reactions strongly depends on such methodology. In this regard, the availability of structurally and electronically diverse phosphorus ligands is essential to fully explore the relationship between […]
Read MoreInCatT is expanding infrastructure
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A new AMTECH SPR16 robot platform is currently being installed. The AMTECH SPR16 is a reaction platform for parallel testing of homogeneous and heterogeneous catalytic reactions. The 16 independent reactors can be programmed individually in terms of reaction temperature, pressure and stirring speed allowing to screen a significant reaction space in a single overnight experiment. […]
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