Tag Archives: catalyst technologies

Switching the acid, one palladium catalyst swaps between alkyne hydroformylation or semihydrogenation (an article review)

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In drug discovery, chemodivergent reactions have recently attracted great interest because of their involvement in the synthesis of libraries of small molecules. The concept of diversity-oriented synthesis relates to the selective formation of various well-defined products from only one readily available starting material. This can be achieved by steering the reaction’s selectivity through fine-tuning of […]

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Scientists make supramolecular iridium catalyst with enzyme-like precise conversions

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By Sander Kluwer, InCatT B.V. The conversion of feedstocks to useable chemical compounds is at the heart of chemistry and the chemical industry. Many catalytic transformations have been developed in the last decades to mature processes. Despite numerous efforts, there were always a number transformations that remained a tough nut to crack. One such conversion […]

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InCatT’s scale up studies using DoE and kinetics – a powerful combination

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The scale up of a reaction from gram to multi-kilogram scale is not always straightforward and requires crucial knowledge about the reaction. One way of upscaling is to perform One Factor At a Time (OFAT) but this only provides very limited information about the reaction space. More appropriate is the statistical DoE (design of experiment) […]

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Robust Highly-Dispersed Heterogeneous Ruthenium Catalysts – Just Add a Pinch of Sodium (article review)

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The importance of heterogeneous catalytic hydrogenation reactions cannot be overemphasized and is one of the backbones of the chemical industry. Highly active and robust catalysts remain an objective particularly from an economical point of view. Catalyst deactivation, the loss over time of catalytic activity and/or selectivity, is a problem of great and continuing concern in […]

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