The selection of the proper catalyst for a new process is not straightforward. Particularly in the field of chiral catalysis, the need for catalyst screening is essential to identify the most active and selective catalyst for the enantioselective transformation. The push to shorten development times, InCatT uses different robotic platforms to speed up the catalyst identification process.
Every catalyst screening is tailor-made to the requirements of the customer. Requirements like use of off-patent catalyst, cheap catalysts, screen commercial or in-house catalysts are all possible. Besides catalyst screening, we also offer our high pressure infrastructure (20 Liter autoclave) for third party production campaigns.
InCatT has developed its’ own privileged catalysts for asymmetric hydrogenation. The METAMORPhos ligands and UREAPhos ligands show great potential for some of the most challenging substrates in asymmetric hydrogenation. With our own developed catalyst systems we have developed production processes to obtain unnatural (fluorinated) amino acids, β-amino acids, 2-amino tetralins and Roche ester and their derivatives.
InCatT B.V. (short for Innovative Catalyst Technologies) is a privately held company founded in 2009 based in The Netherlands as a spin-off company of the University of Amsterdam. The company has developed in an all-round catalysis research company able to tackle most catalytic problems. Each member of the management team has more than 20 years’ experience in homogeneous catalysis.
I have contacted InCatT B.V. with a request to develop new catalytic
processes based on hydroformylation chemistry for the development of
scalable technology for manufacture of perfumery raw materials. Our
new process should perform in the presence of typical diene poisons
and meet the stringent economical requirements that we have set.
Within just 6 weeks, a robust catalytic conversion was delivered that
met all requirements and scale-up in just 3 months at a manufacturing
partner. After this project we have worked together on many different
catalyst development projects. I really enjoyed InCatT’s
proactive approach to solve problems together with the fast and clear
reporting. InCatT’s customer oriented approach resulted in a fruitful
collaboration over the last years.